Biological Safety Training

It is the policy of the University of Chicago Institutional Biosafety Committee (IBC) that all investigators, technicians and students involved with research activities described on a given IBC Protocol be appropriately trained to mitigate research-associated risks as well as to ensure compliance with applicable local, State and Federal regulations and guidelines. This training will include IBC-mandated training elements, developed and provided by the Biological Safety Team, as well as lab-specific training, provided by the Principal Investigator (PI) for each of his/her IBC research protocols.

IBC-mandated training for each individual listed on an IBC protocol is indicated in Section VI (Laboratory Practices). These courses must be completed prior to commencement of the research described in the IBC protocol.

COURSES INCLUDED:
Biosafety Level 1 and rDNA
Biosafety Level 2 and rDNA
Bloodborne Pathogen for Biomedical Researchers 
Viral Vector 
Biological Toxins 
Biosafety Level 3 Operations

Course Descriptions and Registration

To register for the in-person Comprehensive Biological Safety training, click here. Please note: the full in-person course will satisfy IBC Protocol training requirements, but not the individual courses online

Course Descriptions (In-Person)

Comprehensive Biosafety Training

This 3 hour, IBC-mandated training course covers Biosafety Level 2 and Recombinant DNA, Bloodborne Pathogens for Biomedical Researchers, and Viral Vector training. The beginning of the session will cover the difference between risk groups and biosafety levels, NIH and UChicago Policy on recombinant DNA, work commonly conducted at Biosafety level 2, biosafety cabinets, occupational first aid, biohazard spill response and UChicago's Code of Conduct for researchers. This will be followed with Bloodborne Pathogen training which will discuss OSHA standards for handling bloodborne pathogens (BBP) and includes the epidemiology and symptoms of BBP diseases, transmission, and UChicago's exposure control program that covers housekeeping, spill response, personal protective equipment (PPE) and disposal of waste. The course will end with an overview of common viral vectors used in research laboratories such as baculovirus, murine retroviruses, adenovirus, adeno-associated virus (AAV), and lentivirus and their mechanisms of entry into a host cell. Individuals who complete this course will receive credit for all three training modules.

Individual Course Descriptions (Online)

Biosafety Level 1 and Recombinant DNA

This course covers the difference between risk groups and biosafety levels, NIH and UChicago Policy on recombinant DNA, work commonly conducted at Biosafety level 1, and UChicago’s Code of Conduct for researchers. This course can be completed online via EHSA.

Training slides are available for download in PDF form by clicking Biosafety Level 1 and rDNA Training Slides.pdf

Biosafety Level 2 and Recombinant DNA

This course covers the difference between risk groups and biosafety levels, NIH and UChicago Policy on recombinant DNA, work commonly conducted at Biosafety level 2, biosafety cabinets, occupational first aid, biohazard spill response and UChicago’s Code of Conduct for researchers. This course can be completed online via EHSA or through a classroom-based session. The classroom style session combines Biosafety Level 2 training with Bloodborne Pathogen and Viral Vector training. Individuals who attend the classroom session will gain credit for all three modules. To register for a classroom session, please visit EHSA.

Training slides are available for download in PDF form by clicking Biosafety Level 2 and rDNA Training.pdf

Bloodborne Pathogen for Biomedical Researchers

This course covers OSHA standards for handling bloodborne pathogens (BBP) and discusses the authoritative role of UChicago EH&S in the enforcement of those standards. Other material includes the epidemiology and symptoms of BBP diseases, transmission, and UChicago’s exposure control program that covers housekeeping, spill response, personal protective equipment (PPE) and disposal of waste. This course can be completed online via EHSA or through a classroom-based session. The classroom session combines BBP training with Biosafety level 2 and Viral Vector training. Individuals who attend the classroom session will gain credit for all three modules. To register for a classroom session, please visit EHSA.

Training slides are available for download in PDF form by clicking BBP training slides.pdf.

Viral Vectors

This course provides an overview of common viral vectors used in research laboratories such as baculovirus, murine retroviruses, adenovirus, adeno-associated virus (AAV), and lentivirus and their mechanisms of entry into a host cell. This course can be completed online via EHSA or through a classroom-based session. The classroom version combines Viral Vector training with Biosafety Level 2 and Bloodborne Pathogen training. Individuals who attend the classroom session will gain credit for all three modules. To register for a classroom session, please visit EHSA.

Training slides are available for download in PDF form by clicking Viral Vector Training Slides.pdf.

Comparison Table of 1st, 2nd and 3rd generation Lentiviral vectorsLentiviral_vector_comparison.jpeg

Biological Toxins

This course covers the definition of biological toxins, the regulation of toxins, safety, security, decontamination methods and occupational health in relation to working with biological toxins. To complete online, please visit EHSA.

Training slides are available for download in PDF form by clicking Biological Toxins.pdf.

Biosafety Level 3 Operations

This course is only available on an as-needed basis to individuals that will work with select agents required to be handled in a biosafety level 3 facility. After clearance is granted, individuals needing this training should contact the Biological Safety Team for availability and planning.